Issue
Salesforce will begin to require all Salesforce orgs to use a My Domain deployed by the Winter '22 release and enable enhanced domains by the Summer '22 release. Will I need to reauthorize Heroku Connect after enabling My Domain/Enhanced Domain features for Salesforce?
Resolution
No, there shouldn't be any issues using the My Domain/Enhanced Domain features along with Heroku Connect. However, in the event that you encounter Salesforce authorization issues, re-authorizing Salesforce should resolve them.